Rinderpest Immunity in Calves: II. Active Immunization

Active Immunization of Cattle with Killed Vaccines Prepared from Cell Cultured Rinderpest Virus

Active immunization of cattle with killed vaccines prepared from cell-cultured Rinderpest virus.

Cell cultured rinderpest virus inactivated by treatment with 0.01% merthiolate or 0.013% formaldehyde or by exposure to ultraviolet light induced the production of transient neutralizing antibodies in cattle. The addition of aluminium hydroxide or incomplete Freund's adjuvant significantly enhanced neutralizing antibody titres whereas the addition of saponin dramatically depressed the titres. T...

The immunization of cattle against rinderpest in eighteenth-century Europe.

Rinderpest is caused by a morbillivirus closely related to the measles and canine distemper viruses. The pathology and symptomatology of the three diseases are very similar,1 but in terms of mortality, rinderpest is by far the most lethal; in European cattle the death rate often exceeds 80 per cent. The disease was eradicated in Europe over a hundred years ago, but in the eighteenth century an ...

Human Immunization, to Acquire Active Immunity against Snake Venom

heterologous immunity studies in calves in iran

in a series of heterologous immunity studies s. haematobium, s. bovis and o. turkestanicum in calves, a large number of s. haematobium cercariae (21,000 cercariae) were used repeatedly as the immunization agent. at autopsy, 22 weeks after initial exposure, immature s. haematobium was detected. thirteen weeks after initial exposure a group of calves was challenged with s. bovis and another group...